Collect. Czech. Chem. Commun.
1979, 44, 2556-2562
https://doi.org/10.1135/cccc19792556
Synthesis and some biological properties of amides derived from [4-glutamic acid]deamino-1-carba-oxytocin
Michal Lebl, Anastasia Dimeli, Vera Bojanovska, Jiřina Slaninová, Tomislav Barth and Karel Jošt
Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
A number of amides of [4-glutamic acid]deamino-1-carba-oxytocin, as well as certain derivatives of amino acids, and a protected hydrazide of the above-mentioned peptide were prepared by a reaction with the amino-component, using dicyclohexylcarbodiimide and 1-hydroxybenzotriazole. The analogues were checked for uterotonic and galactogogic activity.
