Collect. Czech. Chem. Commun.
1981, 46, 2709-2715
https://doi.org/10.1135/cccc19812709
The synthesis of cyclopentane derivatives with a relation to prostanoic acid
Stanislav Doležal and Jiří Jarý
Laboratory of Monosaccharides, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
A synthesis of 2-(ω-acetoxyalkyl)-2-cyclopenten-1-ones II was worked out. By radical addition of alkanoic acids to cyclopentenones II and to esters of ω-(2-oxo-5-cyclopentenyl)alkanoic acids III 2-[3-oxo-2-(ω-acetoxyalkyl)cyclopentyl]alkanoic acids V and/or esters of ω-[5-(1-carboxyalkyl)-2-oxocyclopentyl]alkanoic acids IV were prepared. The homologues and norderivatives of prostanoic acid prepared were isolated by preparative chromatography on silica gel and their 1H NMR and IR spectra measured.
