Collect. Czech. Chem. Commun.
1982, 47, 2814-2823
https://doi.org/10.1135/cccc19822814
Sequential studies on peptides prepared by chymotryptic digestion of chicken pepsinogen and partial covalent structure of the protein
Miroslav Baudyš and Vladimír Kostka
Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
The peptides obtained by chymotryptic digestion of the S-sulfo derivative of chicken pepsinogen and of the large tryptic fragments of the same derivative were subjected to sequential analysis. The results obtained afforded information on nonoverlapping sequences of 329 amino acid residues in the molecule of the zymogen and yielded data on links between individual fragments in the middle part of the chain obtained in earlier work. A partial covalent structure of the protein is presented which contains 356 amino acid residues in eight segments of uninterchangeable order.
