Collect. Czech. Chem. Commun.
1985, 50, 1862-1869
https://doi.org/10.1135/cccc19851862
Cyclocondensation reactions of 3-aryl-2-benzylidene-3-oxopropanenitriles with acetylaromatic derivatives
Štefan Marchalín and Josef Kuthan
Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6
Abstract
Cyclocondensation of 3-aryl-2-benzylidene-3-oxopropanenitriles Ia and Ib with acetyl aromatic derivatives IIa-IIc in the presence of ammonium acetate affords 2,6-diaryl-4-phenyl-3-cyanopyridines IV and V. Reaction of the nitrile Ib with 1,2-diphenylethanone (III) gave 2-(4-biphenylyl)-4,5,6-triphenyl-3-cyanopyridine (VI). The relation between the structure of the synthesized pyridine derivatives IV-VI and their spectral properties is discussed.
