Collect. Czech. Chem. Commun. 1986, 51, 106-111
https://doi.org/10.1135/cccc19860106

Electrophilic substitution reactions of furo[3,2-b]pyrrole derivatives

Eva Kraľovičová, Alžbeta Krutošíková, Jaroslav Kováč and Miloslava Dandárová

Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava

Abstract

Formylation of ethyl 4H-furo[3,2-b]pyrrole-5-carboxylate and its N-methyl analogue afforded the 2-formyl products Ia,b which on nitration yielded 2-nitro derivatives IIc,d. Formylation, nitration, Mannich reaction, and copulation of the starting products, having position 2 occupied by an aryl, took place at the pyrrole ring.