Collect. Czech. Chem. Commun.
1987, 52, 742-751
https://doi.org/10.1135/cccc19870742
Synthesis and spectral properties of substituted 1,4-dihydropyridines and 1,4,5,6,7,8-hexahydroquinolines
Pavol Čupka, Juraj Bella and Augustin Martvoň
Drug Research Institute, Modra, 811 04 Bratislava
Abstract
Cyclocondensation of 5-nitrophenyl-2-furaldehydes or 5-nitrophenyl-2-thiophenecarbaldehydes with acetoacetates and ammonia in organic solvents afforded 1,4-dihydropyridine derivatives, with 3-aminocrotonates and dimedone the former yielded 1,4,5,6,7,8-hexahydroquinoline derivatives. Relation between the structure and spectral properties is discussed.
