Collect. Czech. Chem. Commun. 1995, 60, 2137-2146
https://doi.org/10.1135/cccc19952137

Synthesis and Some Reactions of 3-Substituted 1,4-Bis(4-hydroxy-2-oxo-1,2-dihydroquinolin-6-yloxy)butanes

Antonín Kláseka, Stanislav Kafkaa and Thomas Kappeb

a Department of Environmental Chemistry and Technology, Technical University of Brno, 762 72 Zlín, Czech Republic
b Institute of Organic Chemistry, University of Graz, A-8010 Graz, Austria

Abstract

Condensations of 1,4-bis(4-aminophenoxy)butane Ia and its N,N'-dimethyl derivative Ib with substituted diethyl malonates gave 1,4-bis(4-hydroxy-2-oxo-1,2-dihydroquinolin-6-yloxy)butanes IIa-IIf. From these compounds, 1,4-bis(3-halogeno-2,4-dioxo-1,2,3,4-tetrahydroquinolin-6-ylox y)butanes IIIa-IIIg and 1,4-bis(3-hydroxy-2,4-dioxo-1,2,3,4-tetrahydroquinolin-6-yloxy )butanes IIIh-IIIm were prepared.