Collect. Czech. Chem. Commun. 1999, 64, 1211-1252
https://doi.org/10.1135/cccc19991211

Biological Function and Chemistry of Endothelin. A Review

Jan Hlaváček* and Renáta Marcová

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Flemingovo nám. 2, Czech Republic

Individual author index pages


Other CCCC articles of these authors

  • Václav Kašička, Zdeněk Prusík, Petra Sázelová, Dušan Koval, Tomislav Barth, Jan Hlaváček, Jan Ježek, Lenka Klasová, Jiřina Slaninová, Jiří Velek and Pavel Vepřek
    Analytical and preparative separations of biologically active peptides by capillary and free-flow electromigration methods
    Symposium Series 2001, Vol. 4, pp. 106–108 [Abstract]
    Published online 2016-04-21 09:04:36
  • Richard Tykva, Petr Šimek, Blanka Bennettová, Josef Holík, Jan Hlaváček and Libor Havlíček
    Conditions for following the metabolism of oostatic peptides in Neobellieria bullata by mass spectrometry and radiolabelling
    Symposium Series 2001, Vol. 4, pp. 93–97 [Abstract]
    Published online 2016-04-21 09:04:22
  • Martina Vojtěchová, Zdena Tuháčková, Jan Hlaváček and Vlasta Sovová
    Transformation of hamster fibroblasts by v-Src resulted in increased activity of both Src and Csk protein kinases
    Symposium Series 2001, Vol. 4, pp. 72–76 [Abstract]
    Published online 2016-04-21 09:03:56
  • Jan Hlaváček, Jiřina Slaninová and Ulf Ragnarsson
    Synthetic study in the oxytocin field
    Symposium Series 2001, Vol. 4, pp. 45–48 [Abstract]
    Published online 2016-04-21 09:03:22
  • Jan Mařík, Miloš Buděšínský, Jiřina Slaninová and Jan Hlaváček
    Biologically inactive methylene-oxy analogs of oxytocin and vasopressin
    Symposium Series 2001, Vol. 4, pp. 26–27 [Abstract]
    Published online 2016-04-21 09:02:59
  • Jan Mařík and Jan Hlaváček
    Synthesis of methylene-oxy pseudodipeptides containing analogs of aspartic acid
    Symposium Series 1999, Vol. 3, pp. 106–108 [Abstract]
    Published online 2016-03-16 22:55:53
  • Václav Kašička, Zdeněk Prusík, Petra Sázelová, Jan Ježek, Jiří Jiráček, Jan Hlaváček, Jiří Velek and Tomislav Barth
    Qualitative and quantitative microanalysis and preparative purification of biopeptides by capillary and continuous free-flow electrophoresis
    Symposium Series 1999, Vol. 3, pp. 100–102 [Abstract]
    Published online 2016-03-16 22:55:44
  • Jan Hlaváček, Jan Mařík, Blanka Bennettová and Richard Tykva
    Proline-rich peptides
    Symposium Series 1999, Vol. 3, pp. 61–64 [Abstract]
    Published online 2016-03-16 22:54:46
  • Richard Tykva, Blanka Bennettová, Jan Hlaváček and Václav Němec
    The fate of an oostatic peptide or its analogs including metabolites in insects Diptera and Orthoptera and its transformation to the next generation
    Symposium Series 1999, Vol. 3, pp. 57–60 [Abstract]
    Published online 2016-03-16 22:54:41
  • Zdena Tuháčková, Eva Šloncová, Jan Hlaváček, Vlasta Sovová and Jiří Velek
    Activation of the protein kinase B and glycogen synthase kinase-3 signalling pathway during transient differentiation of human colon cancer HT-29 cells
    Symposium Series 1999, Vol. 3, pp. 19–22 [Abstract]
    Published online 2016-03-16 22:53:40
  • Martina Vojtěchová, Zdena Tuháčková, Jan Hlaváček, Jiří Velek and Vlasta Sovová
    The v-Src and c-Src tyrosine kinases immunoprecipitated from Rous sarcoma virus-transformed cells display different specificities to three commonly used peptide substrates
    Symposium Series 2003, Vol. 6, pp. 119–121 [Abstract]
    Published online 2016-01-17 20:57:06
  • Veronika Šolínová, Václav Kašička, Dušan Koval, Jan Hlaváček, Tomislav Barth, Alice Ciencialová, Lenka Klasová and Jana Straková
    Analysis of peptides by capillary zone electrophoresis and micellar electrokinetic chromatography
    Symposium Series 2003, Vol. 6, pp. 105–108 [Abstract]
    Published online 2016-01-17 20:56:44
  • Jaroslav Šebestík, Jan Hlaváček and Ivan Stibor
    May bis-intercalator peptides influence prion aggregation?
    Symposium Series 2003, Vol. 6, pp. 98–101 [Abstract]
    Published online 2016-01-17 20:56:34
  • Petr Niederhafner, Martin Šafařík and Jan Hlaváček
    Synthesis of the bis-cystinyl fragment 225-232/225'-232' of the human IgGl hinge region
    Symposium Series 2003, Vol. 6, pp. 61–64 [Abstract]
    Published online 2016-01-17 20:55:49
  • Václav Němec, Blanka Bennettová, Jan Hlaváček and Richard Tykva
    Comparison of biological effects of oostatic tetrapeptide (H-Tyr-Asp-Pro-Ala-OH) and pentapeptide (H-Tyr-Asp-Pro-Ala-Pro-OH) on three types of insect ovaries
    Symposium Series 2003, Vol. 6, pp. 58–60 [Abstract]
    Published online 2016-01-17 20:55:45
  • Elšan S. Nazarov, Josef Holík, Richard Tykva, Jan Hlaváček, Blanka Bennettová and Jiřina Slaninová
    Binding sites for oostatic peptides in organs of fly Neobellieria bullata
    Symposium Series 2003, Vol. 6, pp. 56–57 [Abstract]
    Published online 2016-01-17 20:55:39
  • Jan Hlaváček, Blanka Bennettová, Bohuslav Černý, Věra Vlasáková, Jiřina Slaninová, Josef Holík and Richard Tykva
    Synthesis and utilization of peptides containing 3,4-dehydroproline
    Symposium Series 2005, Vol. 8, pp. 28–32 [Abstract]
    Published online 2015-11-06 12:02:29
  • Petr Niederhafner, Martin Šafařík and Jan Hlaváček
    Synthesis of bis-cystinyl fragment of human IgGl hinge region on PEG using enzymatically cleavable linker
    Symposium Series 2005, Vol. 8, pp. 54–55 [Abstract]
    Published online 2015-11-06 12:01:43
  • Jaroslav Šebestík, Jan Hlaváček and Ivan Stibor
    Rational design of bis-acridine peptide dsDNA binder
    Symposium Series 2005, Vol. 8, pp. 77–79 [Abstract]
    Published online 2015-11-06 12:00:36
  • Veronika Šolínová, Václav Kašička, Dušan Koval, Jan Hlaváček and Tomislav Barth
    Investigation of structure–mobility relationships and estimation of secondary structure of biopeptides by capillary zone electrophoresis
    Symposium Series 2005, Vol. 8, pp. 80–83 [Abstract]
    Published online 2015-11-06 12:00:28
  • Richard Tykva, Jiřina Slaninová, Blanka Bennettová, Jan Hlaváček, Bohuslav Černý, Věra Vlasáková and Václav Němec
    Metabolic cleavage of N- and C-terminal amino acids of an insect oostatic peptide H-Tyr-Asp-Pro-Ala-Pro-OH
    Symposium Series 2005, Vol. 8, pp. 100–102 [Abstract]
    Published online 2015-11-06 11:59:35
  • Jan Hlaváček, Blanka Bennettová, Jiřina Slaninová, Bohuslav Černý, Věra Vlasáková, Josef Holík, Rudolf Ježek and Richard Tykva
    Distribution and degradation of oostatic peptides in the flesh fly Neobellieria bullata
    Symposium Series 2007, Vol. 9, pp. 56–59 [Abstract]
    Published online 2015-11-06 11:55:56
  • Václav Němec, Richard Tykva, Jan Hlaváček and Josef Holík
    Sterilizing effect of an oostatic pentapeptide on reproduction of Pyrrhocoris apterus
    Symposium Series 2007, Vol. 9, pp. 75–79 [Abstract]
    Published online 2015-11-06 11:55:04
  • Jaroslav Šebestík, Alexandr Pavlíček, Martin Šafařík, Karel Holada, Jan Hlaváček and Ivan Stibor
    Acridine nucleophilic displacement – possible culprit of acridine interaction with prion protein
    Symposium Series 2007, Vol. 9, pp. 93–95 [Abstract]
    Published online 2015-11-06 11:54:20
  • Jan Žďárek, Jan Hlaváček and Peter Takáč
    Delayed effects of a dipteran oostatic hormone on reproduction in the tsetse fly
    Symposium Series 2009, Vol. 11, pp. 139–142 [Abstract]
    Published online 2015-08-26 09:43:32
  • Jan Hlaváček, Jan Pícha, Václav Vaněk, Jiří Jiráček, Jiřina Slaninová, Vladimír Fučík, Danuta Gilner and Richard C. Holc
    Analogues of Orn and DAP as potential inhibitors of bacterial enzymes ArgE and DapE
    Symposium Series 2009, Vol. 11, pp. 43–46 [Abstract]
    Published online 2015-08-26 09:41:24
  • Miloslava Vítovcová, Jan Hlaváček, Jan Pícha, Václav Vaněk, Jiří Jiráček and Václav Kašička
    Capillary electrophoresis applied to analysis and characterization of mono-N-acyl-2,6-diaminopimelic acid derivatives
    Symposium Series 2011, Vol. 13, pp. 159–162 [Abstract]
    Published online 2015-07-15 10:17:22
  • Jaroslav Šebestík, Zbigniew Zawada, Martin Šafařík and Jan Hlaváček
    Synthetic scan of C-domain from prion proteins
    Symposium Series 2011, Vol. 13, pp. 148–150 [Abstract]
    Published online 2015-07-15 10:17:00
  • Václav Kašička, Dušan Koval, Sille Ehala, Petra Sázelová, Veronika Šolínová and Jan Hlaváček
    Recent applications of capillary electrophoresis to analysis and physicochemical characterization of peptides
    Symposium Series 2011, Vol. 13, pp. 61–66 [Abstract]
    Published online 2015-07-15 10:12:30
  • Josef Kapitán, Vladimír Baumruk, Vladimír Gut, Jan Hlaváček, Helena Dlouhá, Marie Urbanová, Erich Wünsch and Petr Maloň*
    Raman Optical Activity of the Central Part of Hinge Peptide
    2005, Vol. 70, Issue 4, pp. 403–409 [Abstract]
  • Petr Maloň*, Helena Dlouhá, Blanka Bennettová, Richard Tykva and Jan Hlaváček
    Circular Dichroism and Conformation of Oostatic Peptides: The Carrier-Like Role of C-Terminal Oligoproline Sequence
    2003, Vol. 68, Issue 7, pp. 1309–1318 [Abstract]
  • Jan Mařík, Miloš Buděšínský, Jiřina Slaninová and Jan Hlaváček*
    Synthesis, Bioassay and NMR Study of Methyleneoxy Isosters of Oxytocin and Vasopressin
    2002, Vol. 67, Issue 3, pp. 373–392 [Abstract]
  • Jan Hlaváček*, Renáta Marcová, Miloš Buděšínský and Jiřina Slaninová
    1-Deamino-1(15)-carba and -Dicarba Analogues of Endothelin-1
    2000, Vol. 65, Issue 3, pp. 407–424 [Abstract]
  • Jan Hlaváček, Renáta Marcová, Lenka Maletínská and Jiřina Slaninová
    Analogues of the Cholecystokinin C-Terminal Tetrapeptide
    1994, Vol. 59, Issue 11, pp. 2511–2522 [Abstract]
  • Jan Hlaváček, Otto Smékal, Jan Pospíšek and Tomislav Barth
    Synthesis of Peptides Influencing Growth Hormone Release
    1994, Vol. 59, Issue 3, pp. 707–717 [Abstract]
  • Jan Hlaváček, Jana Pírková, Miroslava Žertová, Jan Pospíšek, Lenka Maletínská and Jiřina Slaninová
    Cholecystokinin Heptapeptide Analogues with Multiple Modification in Peptide Chain
    1993, Vol. 58, Issue 11, pp. 2761–2765 [Abstract]
  • Jan Hlaváček and Vladimír Král
    An Alternative Synthesis of Ψ(CH2O) Pseudodipeptides
    1992, Vol. 57, Issue 3, pp. 525–530 [Abstract]
  • Jan Hlaváček, Jana Pírková, Pavel Majer, Miroslava Žertová, Lenka Maletínská and Jiřina Slaninová
    Analogues of cholecystokinin methylated in the side chain of carboxyterminal phenylalanine
    1991, Vol. 56, Issue 12, pp. 2991–2998 [Abstract]
  • Jan Hlaváček, Jana Pírková, Jan Pospíšek, Jiřina Slaninová and Lenka Maletínská
    Synthesis and biological properties of cholecystokinin heptapeptide analogues containing D- and L-forms of tert-leucine or neopentylglycine in position 5
    1991, Vol. 56, Issue 10, pp. 2209–2217 [Abstract]
  • Jan Hlaváček, Václav Čeřovský, Jana Pírková, Pavel Majer, Lenka Maletínská and Jiřina Slaninová
    Analogues of the cholecystokinin octapeptide modified in the central part of the molecule
    1991, Vol. 56, Issue 9, pp. 1963–1970 [Abstract]
  • Václav Čeřovský, Jana Pírková, Pavel Majer, Jiřina Slaninová and Jan Hlaváček
    Papain-catalyzed fragment synthesis of protected cholecystokinin derivatives
    1990, Vol. 55, Issue 7, pp. 1873–1882 [Abstract]
  • Jan Hlaváček and Ivo Frič
    The effect of non-coded amino acids on the degradation of oxytocin analogs with α-chymotrypsin
    1989, Vol. 54, Issue 8, pp. 2261–2270 [Abstract]
  • Jan Hlaváček, Ivo Frič, Miloš Buděšínský and Karel Bláha
    An alternative route to Nα-methylamino acid derivatives: Synthesis and conformation of some Nα-acetyl-Nα-methylamino acid methylamides
    1988, Vol. 53, Issue 11, pp. 2473–2494 [Abstract]
  • Václav Čeřovský, Jan Hlaváček, Jiřina Slaninová and Karel Jošt
    Synthesis of the carboxy-terminal octapeptide of cholecystokinin (CKK-8) based on incorporation of O4-sulfotyrosine by enzymatically catalyzed formation of peptide bonds
    1988, Vol. 53, Issue 5, pp. 1086–1093 [Abstract]
  • Jan Hlaváček, Jan Pospíšek, Jiřina Slaninová, Walter Y. Chan and Victor J. Hruby
    Oxytocin analogues with non-coded amino acid residues in position 8: [8-Neopentylglycine]oxytocin and [8-cycloleucine]oxytocin
    1987, Vol. 52, Issue 9, pp. 2317–2325 [Abstract]
  • Jan Hlaváček, Ivo Frič, Petr Maloň, Karel Jošt and Karel Bláha
    Three cyclohexapeptides modelling the oxytocin ring moiety: Synthesis and circular dichroism
    1987, Vol. 52, Issue 7, pp. 1841–1856 [Abstract]
  • Zdenko Procházka, Michal Lebl, Tomislav Barth, Jan Hlaváček, Antonín Trka, Miloš Buděšínský and Karel Jošt
    Synthesis and properties of oxytocin analogues modified in the tripeptide side chain
    1984, Vol. 49, Issue 3, pp. 642–652 [Abstract]
  • Petr Maloň, Petr Pančoška, Miloš Buděšínský, Jan Hlaváček, Jan Pospíšek and Karel Bláha
    Chiroptical properties and conformation of N-acetyl-L-amino acids N'-methylamides with aliphatic side chains
    1983, Vol. 48, Issue 10, pp. 2844–2861 [Abstract]
  • Michal Lebl, Jan Pospíšek, Jan Hlaváček, Tomislav Barth, Petr Maloň, Linda Servítová, Karel Hauzer and Karel Jošt
    Analogues of neurohypophysial hormones, containing tert-leucine: Synthesis and properties
    1982, Vol. 47, Issue 2, pp. 689–701 [Abstract]
  • Jan Hlaváček, Ivo Frič, Tomislav Barth and Karel Jošt
    [9-Aminoacetone]oxytocin and [8-p-aminobenzamide, 9-des-glycinamide]oxytocin: Chemical synthesis and properties
    1982, Vol. 47, Issue 1, pp. 338–348 [Abstract]
  • Jan Hlaváček, Tomislav Barth, Karel Bláha and Karel Jošt
    Synthesis of oxytocin analogues modified in the tripeptide side-chain by condensation of aminoterminal linear hexapeptide with the carboxyterminal tripeptide
    1979, Vol. 44, Issue 1, pp. 275–287 [Abstract]