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Collect. Czech. Chem. Commun. 2000, 65, 1653-1668
https://doi.org/10.1135/cccc20001653

Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells

Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic

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  • Sigel Astrid, Operschall Bert P., Sigel Helmut: Comparison of the π-stacking properties of purine versus pyrimidine residues. Some generalizations regarding selectivity. J Biol Inorg Chem 2014, 19, 691. <https://doi.org/10.1007/s00775-013-1082-5>
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  • Ray Adrian S, Myrick Florence, Vela Jennifer E, Olson Loren Y, Eisenberg Eugene J, Borroto-Esoda Katyna, Miller Michael D, Fridland Arnold: Lack of a Metabolic and Antiviral Drug Interaction between Tenofovir, Abacavir and Lamivudine. Antiviral Therapy 2005, 10, 451. <https://doi.org/10.1177/135965350501000308>
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  • Krejcova Romana, Horska Kvetoslava, Votruba Ivan, Holy Antonin: ChemInform Abstract: Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells. ChemInform 2001, 32. <https://doi.org/10.1002/chin.200114230>
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