Collect. Czech. Chem. Commun.
2001, 66, 1831-1840
https://doi.org/10.1135/cccc20011831
Synthesis of Some Steroidal Oxazolines
János Wölfling, Erzsébet Mernyák, Melinda Sebők and Gyula Schneider*
Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, Hungary
Abstract
Steroidal oxazolines 4a-4d and 5a-5f were synthesized. The acid-catalyzed reactions of 21-azido-20-hydroxy- and 21-hydroxy-20-azidosteroids with substituted aromatic aldehydes led to the formation of androst-5-en-3β-ols substituted in position 17β with oxazoline residues.
Keywords: Steroids; Vicinal-azidoalcohols; Oxazolines; Schmidt reaction.
References: 13 live references.
