Collect. Czech. Chem. Commun.
2006, 71, 1199-1210
https://doi.org/10.1135/cccc20061199
A New Stereocontrolled Approach to a Key Intermediate in the Synthesis of (2S,3R)-Capreomycidine
Miroslava Martinkováa,*, Jozef Gondaa and Martina Džoganováb
a Department of Organic Chemistry, Institute of Chemistry, P. J. Šafárik University, 041 67 Košice, Slovak Republic
b Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic
Abstract
A new stereocontrolled approach to the synthesis of advanced intermediate in the synthesis of nonproteinogenic amino acid (2S,3R)-capreomycidine via the novel domino reaction has been developed.
Keywords: Capreomycidine; Capreomycins; Stereoselectivity; Nonproteinogenic amino acids; [3,3]-Sigmatropic rearrangements; Total synthesis.
References: 27 live references.
