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Collect. Czech. Chem. Commun. 2010, 75, 1249-1257
https://doi.org/10.1135/cccc2010094
Published online 2010-11-23 08:48:56

Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners

Ivan Votruba*, Jana Trýznová, Petra Břehová, Eva Tloušťová, Květoslava Horská, Jindřich Fanfrlík, Ondřej Přenosil and Antonín Holý

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Gilead Sciences & IOCB Research Centre, Centre for New Antivirals and Antineoplastics (IOCB), Center for Biomolecules and Complex Molecular Systems, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic

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  • Krečmerová Marcela, Majer Pavel, Rais Rana, Slusher Barbara S.: Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects. Front. Chem. 2022, 10. <https://doi.org/10.3389/fchem.2022.889737>
  • Baszczyňski Ondřej, Janeba Zlatko: Medicinal Chemistry of Fluorinated Cyclic and Acyclic Nucleoside Phosphonates. Medicinal Research Reviews 2013, 33, 1304. <https://doi.org/10.1002/med.21296>
  • Špak Josef, Votruba Ivan, Pavingerová Daniela, Holý Antonín, Špaková Vlastimila, Petrzik Karel: Antiviral activity of tenofovir against Cauliflower mosaic virus and its metabolism in Brassica pekinensis plants. Antiv Res 2011, 92, 378. <https://doi.org/10.1016/j.antiviral.2011.08.014>