Collect. Czech. Chem. Commun.
2010, 75, 665-673
https://doi.org/10.1135/cccc2009545
Published online 2010-06-17 08:31:59
Biotransformation of some steroids by Aspergillus terreus MRC 200365
Kudret Yildirim*, Ahmet Uzuner and Emine Yasemin Gulcuoglu
Chemistry Department, Sakarya University, 54187, Sakarya, Turkey
Abstract
The biotransformations of testosterone, epiandrosterone, progesterone and pregnenolone by Aspergillus terreus MRC 200365 for five days were described. The biotransformation of testosterone afforded testolactone. The biotransformation of epiandrosterone afforded 3β-hydroxy-17a-oxa-D-homo-5α-androstan-17-one. The biotransformation of progesterone afforded androst-4-ene-3,17-dione and testolactone. The biotransformation of pregnenolone afforded 3β-hydroxy-17a-oxa-D-homoandrost-5-en-17-one and testolactone.
Keywords: Steroids; Biotransformations; Xenobiotics; Aspergillus terreus.
References: 38 live references.
