Collect. Czech. Chem. Commun. 2010, 75, 887-903
https://doi.org/10.1135/cccc2010048
Published online 2010-08-31 09:18:53

Glyoxyl analogs of indole phytoalexins: Synthesis and anticancer activity

Peter Kutschya,*, Andrej Sýkorab, Zuzana Čurillováa, Mária Repovskáa, Martina Pilátovác, Ján Mojžišc, Roman Mezencevd, Pavel Pazderae and Tatiana Hromjákováa

a P. J. Šafárik University, Faculty of Science, Institute of Chemical Sciences, Department of Organic Chemistry, Moyzesova 11, 040 01 Košice, Slovak Republic
b University of Prešov, Faculty of Health Care, Partizánska 1, 080 01 Prešov, Slovak Republic
c P. J. Šafárik University, Faculty of Medicine, Department of Pharmacology, SNP 1, 040 66 Košice, Slovak Republic
d Georgia Institute of Technology, College of Science, School of Biology, 315 Ferst Drive, Atlanta, GA 30332, USA
e Centre for Syntheses at Sustainable Conditions and Their Management, Department of Chemistry, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic

Individual author index pages


Other CCCC articles of these authors

  • Richard Čmelík and Pavel Pazdera*
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  • Martin Humeník*, Peter Kutschy, Vladimír Kováčik and Slávka Bekešová
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    2005, Vol. 70, Issue 4, pp. 487–506 [Abstract]
  • Martin Humeník*, Peter Kutschy, Katarína Valková, Branislav Horváth, Vladimír Kováčik and Slávka Bekešová
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    2005, Vol. 70, Issue 1, pp. 72–84 [Abstract]
  • Martin Humeník*, Milan Dzurilla, Peter Kutschy, Eva Solčániová, Vladimír Kováčik and Slávka Bekešová
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    2004, Vol. 69, Issue 8, pp. 1657–1674 [Abstract]
  • Peter Kutschy*, Marian Sabol, Renata Marušková, Zuzana Čurillová, Milan Dzurilla, Imrich Géci, Juraj Alföldi and Vladimír Kováčik
    A Linear Synthesis of 1-(β-D-Glucopyranosyl)brassinin, -brassenin A, -brassenin B and 9-(β-D-Glucopyranosyl)cyclobrassinin
    2004, Vol. 69, Issue 4, pp. 850–866 [Abstract]
  • Janka Záletová, Milan Dzurilla, Peter Kutschy*, Pavel Pazdera, Vladimír Kováčik, Juraj Aldölfi and Slávka Bekešová
    Synthesis of 4,6-Disubstituted-2-(1H-indol-3-yl)benzothiazoles
    2004, Vol. 69, Issue 2, pp. 453–460 [Abstract]
  • Richard Čmelík, Michal Čajan, Jaromír Marek and Pavel Pazdera*
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    2003, Vol. 68, Issue 7, pp. 1243–1263 [Abstract]
  • Peter Kutschy*, Mojmír Suchý, Milan Dzurilla, Mitsuo Takasugi and Vladimír Kováčik
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    2000, Vol. 65, Issue 7, pp. 1163–1172 [Abstract]
  • Peter Kutschy*, Mojmír Suchý, Milan Dzurilla, Pavel Pazdera, Mitsuo Takasugi and Vladimír Kováčik
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  • Jiří Šibor, Dalimil Žůrek, Radek Marek, Michal Kutý, Otakar Humpa, Jaromír Marek and Pavel Pazdera*
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    1999, Vol. 64, Issue 10, pp. 1673–1695 [Abstract]
  • Milan Dzurilla*, Martin Ružinský, Peter Kutschy, Jalpa P. Tewari and Vladimír Kováčik
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    1999, Vol. 64, Issue 9, pp. 1448–1456 [Abstract]
  • Peter Kutschy*, Milan Dzurilla, Mitsuo Takasugi and Adriana Sabová
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    1999, Vol. 64, Issue 2, pp. 348–362 [Abstract]
  • Milan Dzurilla, Peter Kutschy, Jalpa P. Tewari, Martin Ružinský, Stanislav Šenvický and Vladimír Kováčik
    Synthesis and Antifungal Activity of New Indolylthiazinone Derivatives
    1998, Vol. 63, Issue 1, pp. 94–102 [Abstract]
  • Oľga Hritzová, Gejza Suchár, Ivan Danihel and Peter Kutschy
    Solvent Effect on the Structure and Infrared Spectra of N-(3-Chloro-2-benzo[b]thienocarbonyl)-N'-ethylthiourea
    1996, Vol. 61, Issue 11, pp. 1620–1626 [Abstract]
  • Milan Dzurilla, Peter Kutschy, Ján Imrich and Stanislav Brtoš
    Hugershoff Reaction of N-1- or N-2-Naphthoyl-N'-monosubstituted and N',N'-Disubstituted Thiourea Derivatives
    1994, Vol. 59, Issue 12, pp. 2663–2676 [Abstract]
  • Vlastimír Ficeri, Peter Kutschy, Milan Dzurilla and Ján Imrich
    [3,3]- Versus [1,3]-Sigmatropic Rearrangement of O-Substituted Allyl N-Acylmonothiocarbamates
    1994, Vol. 59, Issue 12, pp. 2650–2662 [Abstract]
  • Marcel Török, Milan Dzurilla, Peter Kutschy, Ján Imrich, Ivan Danihel, Paul Rademacher and Heinz Bandmann
    Cyclohexylideneacetyl Isothiocyanate. Precursor for the Synthesis of 1,3-Thiazaspirocycloalkanes and 1,3-Diazaspirocycloalkanes
    1994, Vol. 59, Issue 5, pp. 1203–1210 [Abstract]
  • Dušan Koščík, Milan Dzurilla and Peter Kutschy
    New Preparation of 2-N-Alkyl(aryl)amino-5-methyl-4H-1,3-thiazin-4-ones and 3,4-Dihydro-5-methyl-2,4-dioxo-2H-1,3-thiazine
    1993, Vol. 58, Issue 4, pp. 893–901 [Abstract]
  • Peter Kutschy, Milan Dzurilla, Vlastimír Ficeri and Dušan Koščík
    New Synthesis of N-Acylurea Derivatives
    1993, Vol. 58, Issue 3, pp. 575–587 [Abstract]
  • Milan Dzurila, Peter Kutschy, Ján Imrich, Dušan Koščík and Robert Kraus
    Cyclization and oxidation of N-substituted phenyl-N’-(2-methyl-3-phenylpropenoyl)thioureas
    1991, Vol. 56, Issue 6, pp. 1287–1294 [Abstract]
  • Milan Dzurilla, Peter Kutschy, Dušan Koščík and Štefan Toma
    Intramolecular cyclization of O-alkyl-N-(3-phenylpropenoyl)thiocarbamates catalyzed by boron trifluoride
    1990, Vol. 55, Issue 3, pp. 710–717 [Abstract]
  • Oľga Hritzová, Peter Kutschy, Ján Imrich and Thomas Schöffmann
    Hydrogen bonds in N-(3-chloro-2-benzo[b]thienocarbonyl)- and N-(2-benzo[b]thienocarbonyl)-N'-monosubstituted thioureas
    1987, Vol. 52, Issue 11, pp. 2673–2679 [Abstract]
  • Milan Dzurilla, Peter Kutschy and Dušan Koščík
    A new method for preparation of 1-(4-substituted phenyl)-6-phenyl-2-thiouracils via cyclization of N-(4-substituted phenyl)-N'-3-phenylpropenoylthioureas and Dimroth rearrangement of 2-(4-substituted phenylimino)-6-phenyl-5,6-dihydro-4H-1,3-thiazin-4-ones
    1987, Vol. 52, Issue 9, pp. 2260–2265 [Abstract]
  • Peter Kutschy, Milan Dzurilla, Dušan Koščík and Pavol Kristian
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    1987, Vol. 52, Issue 7, pp. 1764–1772 [Abstract]
  • Peter Kutschy, Pavol Kristian, Milan Dzurilla, Dušan Koščík and Róbert Nádaskay
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    1987, Vol. 52, Issue 4, pp. 995–1005 [Abstract]
  • Milan Dzurilla, Ondrej Forgáč, Peter Kutschy, Pavol Kristian, Dušan Koščík and Ján Imrich
    Synthesis of 1,3-diazaspiro[5,5]undecanes and 1-thia-3-azaspiro[5,5]undec-2-enes by reaction of 2-cyanocyclohexylideneacetyl isothiocyanate with amines and sodium hydrogen sulfide
    1987, Vol. 52, Issue 4, pp. 989–994 [Abstract]
  • Peter Kutschy, Ján Imrich, Juraj Bernát, Pavol Kristian, Oľga Hritzová and Thomas Schöffmann
    Photocyclization of N-(3-chloro-2-benzo[b]thienocarbonyl)-N'-monosubstituted thioureas
    1986, Vol. 51, Issue 12, pp. 2839–2847 [Abstract]
  • Peter Kutschy, Ján Imrich, Juraj Bernát, Pavol Kristian and Iveta Fedoriková
    A study of photocyclization of O-alkyl N-(3-chloro-2-benzo[b]thienocarbonyl)monothiocarbamates
    1986, Vol. 51, Issue 9, pp. 2002–2012 [Abstract]
  • Peter Kutschy, Milan Dzurilla, Ladislav Kniežo, Juraj Bernát, Ján Imrich, Pavol Kristian and Róbert Nádaskay
    Reactions of 3-butine-2-methyl-2-ol with isothiocyanates
    1986, Vol. 51, Issue 5, pp. 1119–1126 [Abstract]
  • Peter Kutschy, Pavol Kristian, Miloslava Dandárová and Jaroslav Kováč
    Synthesis and reactions of cis-3-(2-furyl)propenoyl isocyanate
    1981, Vol. 46, Issue 5, pp. 1160–1166 [Abstract]
  • Peter Kutschy, Milan Dzurilla, Pavol Kristian and Kvetoslava Kutschyová
    Synthesis of 2-substituted 5-arylidenethiazolin-4-ones from α,β-unsaturated acyl isothiocyanates
    1981, Vol. 46, Issue 2, pp. 436–445 [Abstract]
  • Milan Dzurilla, Pavol Kristian and Peter Kutschy
    Synthesis of 2-amino-6-substituted 5,6-dihydro-4H-1,3-thiazin-4-ones from α,β-unsaturated acyl isothiocyanates
    1980, Vol. 45, Issue 11, pp. 2958–2964 [Abstract]
  • Peter Kutschy, Pavol Kristian, Milan Dzurilla and Jaroslav Kováč
    Reactions of α,β-unsaturated acyl isothiocyanates with phenylhydrazine
    1980, Vol. 45, Issue 6, pp. 1692–1703 [Abstract]
  • Pavol Kristian, Peter Kutschy and Milan Dzurilla
    Synthesis of 2,2,4-trisubstituted 2H-1,3-oxazetes from acyl isothiocyanates
    1979, Vol. 44, Issue 4, pp. 1324–1333 [Abstract]