Collect. Czech. Chem. Commun.
2011, 76, 27-37
https://doi.org/10.1135/cccc2010111
Published online 2010-12-06 09:27:41
An efficient synthesis of 2-arylbenzothiazoles using silica sulfuric acid, oxalic acid and aluminum chloride hydrate as heterogeneous and homogeneous catalyst systems
Behrooz Maleki
Department of Chemistry, Sabzevar Tarbiat Moallem University, 397 Sabzevar, Iran
Abstract
A convenient method for the synthesis of 2-arylbenzothiazoles from condensation of aromatic/heteroaromatic aldehydes with 2-aminothiophenol has been developed using inexpensive, green and reusable solid acids – silica sulfuric acid (SSA), oxalic acid or AlCl3·6H2O as efficient catalysts. The reactions occurred under mild conditions to afford the corresponding 2-arylbenzothiazoles in good to excellent yields.
Keywords: Acidity; Aldehydes; Antibiotics; Antibacterial activity; Antiaromaticity; Antifungal activity; 2-Arylbenzothiazoles; Silica sulfuric acid; Oxalic acid; AlCl3·6H2O; 2-Aminothiophenol.
References: 63 live references.
