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Purines

• Petr Nauš, Pavla Perlíková, Radek Pohl and Michal Hocek*
  Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides
  2011, Vol. 76, Issue 8, pp. 957–988 [Abstract]
• Michal Šála, Hubert Hřebabecký*, Martin Dračínský, Milena Masojídková, Armando M. De Palma, Johan Neyts and Antonín Holý
  Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene
  2010, Vol. 75, Issue 1, pp. 1–20 [Abstract]
• Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2-dimethanol template
  2009, Vol. 74, Issue 9, pp. 1425–1441 [Abstract]
• Zbyněk Hasník, Radek Pohl, Blanka Klepetářová and Michal Hocek*
  Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines
  2009, Vol. 74, Issue 7-8, pp. 1035–1059 [Abstract] [Full text pdf]
• Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
  Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol
  2009, Vol. 74, Issue 3, pp. 487–502 [Abstract]
• Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
  Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.0^3,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.0^3,7]decane-10-methanol, compounds with activity against Coxsackie viruses
  2009, Vol. 74, Issue 3, pp. 469–485 [Abstract]
• Petr Nauš, Martin Kuchař and Michal Hocek*
  Cytostatic and Antiviral 6-Arylpurine Ribonucleosides IX. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides
  2008, Vol. 73, Issue 5, pp. 665–678 [Abstract] [Full text pdf]
• Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol
  2008, Vol. 73, Issue 1, pp. 44–58 [Abstract]
• Milan Dejmek, Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane
  2007, Vol. 72, Issue 11, pp. 1523–1544 [Abstract]
• Tomáš Tobrman and Dalimil Dvořák*
  Reductive Dimerization of 2- and 6-Iodopurines: Side Reaction in Pd-Catalyzed Cross-Coupling of Iodopurines
  2007, Vol. 72, Issue 10, pp. 1365–1374 [Abstract]
• Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
  Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.0^3,7]nonane-9-methanol
  2007, Vol. 72, Issue 10, pp. 1331–1349 [Abstract]
• Michal Hocek*, Peter Šilhár and Radek Pohl
  Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides
  2006, Vol. 71, Issue 10, pp. 1484–1496 [Abstract]
• Michal Česnek*, Milena Masojídková, Antonín Holý, Veronika Šolínová, Dušan Koval and Václav Kašička
  Synthesis and Properties of 2-Guanidinopurines
  2006, Vol. 71, Issue 9, pp. 1303–1319 [Abstract]
• Martin Klečka, Tomáš Tobrman and Dalimil Dvořák*
  Cu(I)-Catalyzed Coupling of (9-Benzylpurin-6-yl)magnesium Chloride with Allyl Halides: An Approach to 6-Allylpurine Derivatives
  2006, Vol. 71, Issue 8, pp. 1221–1228 [Abstract]
• Anastasiya L. Khandazhinskaya, Elena A. Shirokova, Alexander V. Shipitsin, Inna L. Karpenko, Evgenii F. Belanov, Marina K. Kukhanova and Maksim V. Yasko*
  Adenosine N¹-Oxide Analogues as Inhibitors of Orthopox Virus Replication
  2006, Vol. 71, Issue 7, pp. 1107–1121 [Abstract]
• Loredana Cappellacci, Palmarisa Franchetti, Riccardo Petrelli, Sara Riccioni, Patrizia Vita, Hiremagalur N. Jayaram and Mario Grifantini*
  Purine and Pyrimidine Nucleoside Analogs of 3'-C-Methyladenosine as Antitumor Agents
  2006, Vol. 71, Issue 7, pp. 1088–1098 [Abstract]
• Jean-François Griffon, Sue C. Shaddix, William B. Parker, Ashraf S. Al-Madhoun, Staffan Eriksson, John A. Montgomery and John A. Secrist III*
  Synthesis and Biological Evaluation of Some 4'-C-(Hydroxymethyl)-α- and -β-D-Arabinofuranosyl Pyrimidine and Adenine Nucleosides
  2006, Vol. 71, Issue 7, pp. 1063–1087 [Abstract]
• Xiaoyu Lin and Morris J. Robins*
  Nucleic Acid Related Compounds. 136. Synthesis of 2-Amino- and 2,6-Diaminopurine Derivatives via Inverse-Electron-Demand Diels-Alder Reactions
  2006, Vol. 71, Issue 7, pp. 1029–1041 [Abstract]
• Frank Seela* and Xiaohua Peng
  Pyrrolo[2,3-d]pyrimidine β-L-Nucleosides Containing 7-Deazaadenine, 2-Amino-7-deazaadenine, 7-Deazaguanine, 7-Deazaisoguanine, and 7-Deazaxanthine
  2006, Vol. 71, Issue 7, pp. 956–977 [Abstract]
• Pedro Besada, Liaman K. Mamedova, Krishnan K. Palaniappan, Zhan-Guo Gao, Bhalchandra V. Joshi, Lak Shin Jeong, Mortimer M. Civan and Kenneth A. Jacobson*
  Nucleoside Prodrugs of A₃ Adenosine Receptor Agonists and Antagonists
  2006, Vol. 71, Issue 6, pp. 912–928 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková, Martin Dračínský and Antonín Holý
  Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol
  2006, Vol. 71, Issue 6, pp. 871–888 [Abstract]
• Peter Šilhár, Radek Pohl, Ivan Votruba, Blanka Klepetářová and Michal Hocek*
  Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides
  2006, Vol. 71, Issue 6, pp. 788–803 [Abstract]
• Michal Šála, Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo[2.2.1]hept-5-ene-2,2-dimethanols
  2006, Vol. 71, Issue 5, pp. 635–649 [Abstract]
• Alicja Stachelska*, Zbigniew J. Wieczorek, Janusz Stępiński, Marzena Jankowska-Anyszka, Harri Lönnberg and Edward Darżynkiewicz
  Kinetics of the Imidazolium Ring-Opening of mRNA 5'-cap Analogs in Aqueous Alkali
  2006, Vol. 71, Issue 4, pp. 567–578 [Abstract]
• Silvie Vrbovská*, Antonín Holý, Radek Pohl and Milena Masojídková
  Bifunctional Acyclic Nucleoside Phosphonates. 1. Symmetrical 1,3-Bis[(phosphonomethoxy)propan-2-yl] Derivatives of Purines and Pyrimidines
  2006, Vol. 71, Issue 4, pp. 543–566 [Abstract]
• Kateřina Hořejší, Radek Pohl and Antonín Holý*
  Tricyclic Purine Analogs Derived from 2-Amino-6-chloropurine and 2,6-Diaminopurine and Their Methylated Quaternary Salts
  2006, Vol. 71, Issue 1, pp. 77–90 [Abstract]
• Jindřich Fanfrlík, Jaroslav Rejnek, Michal Hanus and Pavel Hobza*
  Hydration Gibbs Energies of Nucleic Acid Bases Determined by Gibbs Energy Perturbation, Continuous and Hybrid Approaches
  2005, Vol. 70, Issue 11, pp. 1756–1768 [Abstract]
• Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek*
  Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides
  2005, Vol. 70, Issue 10, pp. 1669–1695 [Abstract]
• Qiong Luo, Qian Shu Li*, Yaoming Xie and Henry F. Schaefer*
  Radicals Derived from Guanine: Structures and Energetics
  2005, Vol. 70, Issue 6, pp. 826–836 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 5,5- and 6,6-Bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol
  2005, Vol. 70, Issue 4, pp. 519–538 [Abstract]
• Pavel Turek, Martin Kotora*, Michal Hocek* and Ivan Votruba
  Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes
  2005, Vol. 70, Issue 3, pp. 339–349 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Racemic 9-(6- and 2,6-Substituted 9H-Purin-9-yl)-5-oxatricyclo[4.2.1.0^3,7]nonane-3-methanols, Novel Conformationally Locked Carbocyclic Nucleosides
  2005, Vol. 70, Issue 1, pp. 103–123 [Abstract]
• Györgyi Ferenc, Péter Forgó, Zoltán Kele and Lajos Kovács*
  A Regioselective Synthesis of Alkyl 2-(Guanin-9-yl)acetates as PNA Building Blocks from 7-(4-Nitrobenzyl)guanine Derivatives
  2005, Vol. 70, Issue 1, pp. 85–102 [Abstract]
• Petr Nauš, Ivan Votruba and Michal Hocek*
  Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides
  2004, Vol. 69, Issue 10, pp. 1955–1970 [Abstract]
• Marcela Krečmerová*, Milena Masojídková and Antonín Holý
  Synthesis of N⁹- and N⁷-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N⁶-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
  2004, Vol. 69, Issue 10, pp. 1889–1913 [Abstract]
• Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
  Synthesis of Purine Nucleoside Analogues Derived from Carbocyclic 5-C-(Hydroxymethyl)hexopyranoses
  2004, Vol. 69, Issue 2, pp. 435–452 [Abstract]
• Jiří Šponer* and Pavel Hobza*
  Molecular Interactions of Nucleic Acid Bases. A Review of Quantum-Chemical Studies
  2003, Vol. 68, Issue 12, pp. 2231–2282 [Abstract]
• Michal Česnek*, Antonín Holý and Milena Masojídková
  New 2-Alkynyl Derivatives of the Acyclic Nucleoside 9-(2,3-Dihydroxypropyl)adenine and Their 6-Guanidinopurine Counterparts as Potential Effectors of Adenosine Receptors
  2003, Vol. 68, Issue 11, pp. 2201–2218 [Abstract]
• Claudio Fontanesi*, Roberto Andreoli, Luca Benedetti, Roberto Giovanardi and Paolo Ferrarini
  Temperature Effect on the Two-Dimensional Phase Transition Kinetics of Adenine Adsorbed at the Hg Electrode/Aqueous Solution Interface
  2003, Vol. 68, Issue 8, pp. 1407–1419 [Abstract]
• Zdenek Chval and Miroslav Šíp*
  Transition States of Cisplatin Binding to Guanine and Adenine: ab initio Reactivity Study
  2003, Vol. 68, Issue 6, pp. 1105–1118 [Abstract]
• Danuše Tarkowská*, Milan Kotouček and Karel Doležal
  Electrochemical Reduction of 6-Benzylaminopurine at Mercury Electrodes and Its Analytical Application
  2003, Vol. 68, Issue 6, pp. 1076–1093 [Abstract]
• Marcela Krečmerová*, Miloš Buděšínský, Milena Masojídková and Antonín Holý
  Synthesis of Optically Active N⁶-Alkyl Derivatives of (R)-3-(Adenin-9-yl)-2-hydroxypropanoic Acid and Related Compounds
  2003, Vol. 68, Issue 5, pp. 931–950 [Abstract]
• Michal Hocek*, Dana Hocková and Jan Štambaský
  Cytostatic 6-Arylpurine Nucleosides V. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides
  2003, Vol. 68, Issue 5, pp. 837–848 [Abstract]
• Petr Čapek, Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
  A Facile Synthesis of 9-Deaza Analogue of Olomoucine
  2003, Vol. 68, Issue 4, pp. 779–791 [Abstract]
• Michal Hocek*, Hana Dvořáková and Ivana Císařová
  Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected by Diverse Types of Acyclic Carbon Linkages
  2002, Vol. 67, Issue 10, pp. 1560–1578 [Abstract]
• Michal Hocek*, Irena G. Stará, Ivo Starý and Hana Dvořáková
  Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil
  2002, Vol. 67, Issue 8, pp. 1223–1235 [Abstract]
• Cyril Párkányi*, Christian Boniface, Jean-Jacques Aaron, Mihaela Bulaceanu-MacNair and Marwan Dakkouri
  Theoretical and Experimental Dipole Moments of Purines
  2002, Vol. 67, Issue 8, pp. 1109–1124 [Abstract]
• Michal Hocek*, Antonín Holý and Hana Dvořáková
  Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides
  2002, Vol. 67, Issue 3, pp. 325–335 [Abstract]
• František Franěk*, Věra Siglerová, Libor Havlíček, Miroslav Strnad, Tomáš Eckschlager and Evžen Weigl
  Effect of the Purine Derivative Myoseverin and of Its Analogues on Cultured Hybridoma Cells
  2002, Vol. 67, Issue 2, pp. 257–266 [Abstract]
• Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
  Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N⁶-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
  2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract]
• Zlatko Janeba*, Antonín Holý and Milena Masojídková
  Transformation of 8-[(2-Hydroxyalkyl)sulfanyl]adenines to 6-Amino-7H-purin-8(9H)-one Derivatives
  2001, Vol. 66, Issue 9, pp. 1393–1406 [Abstract]
• Zlatko Janeba*, Antonín Holý and Milena Masojídková
  Synthesis of 8-Amino- and N-Substituted 8-Aminoadenine Derivatives of Acyclic Nucleoside and Nucleotide Analogs
  2001, Vol. 66, Issue 3, pp. 517–532 [Abstract]
• Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
  Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
  2001, Vol. 66, Issue 3, pp. 483–499 [Abstract]
• Petr Alexander*, Antonín Holý, Miloš Buděšínský and Milena Masojídková
  Synthesis of Acyclic Nucleotide Analogues Derived from N³-Substituted Isoguanine
  2000, Vol. 65, Issue 11, pp. 1713–1725 [Abstract]
• Zlatko Janeba*, Antonín Holý and Milena Masojídková
  Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purine-8(9H)-thione and 8-(Methylsulfanyl)adenine
  2000, Vol. 65, Issue 11, pp. 1698–1712 [Abstract]
• Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
  Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
  2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract]
• Michal Česnek, Michal Hocek* and Antonín Holý
  Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents
  2000, Vol. 65, Issue 8, pp. 1357–1373 [Abstract]
• Zlatko Janeba*, Antonín Holý and Milena Masojídková
  Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purin-8(9H)-one
  2000, Vol. 65, Issue 7, pp. 1126–1144 [Abstract]
• Kateřina Meszárosová, Antonín Holý* and Milena Masojídková
  Synthesis of Acyclic Adenine 8,N-Anhydronucleosides
  2000, Vol. 65, Issue 7, pp. 1109–1125 [Abstract]
• Martina Havelková, Martin Studenovský and Dalimil Dvořák*
  N¹-Substituted Hypoxanthine Derivatives from the Reaction of 6-Halopurines with Michael Acceptors Under the Conditions of Heck Reaction
  2000, Vol. 65, Issue 5, pp. 797–804 [Abstract]
• Dana Hocková*, Milena Masojídková and Antonín Holý
  7-(1-Cyanobut-3-en-1-yl)-N⁶-[(N,N-dimethylamino)methylene]adenine as a Starting Compound for the Synthesis of α-Branched Acyclic Analogues of N⁷-Isomer of Adenosine
  1999, Vol. 64, Issue 8, pp. 1316–1324 [Abstract]
• Vladimír Tolman*, Jan Hanuš and Petr Sedmera
  A Hetero Diels-Alder Access to (Z)-Zeatin and (Z)-Isozeatin
  1999, Vol. 64, Issue 4, pp. 696–702 [Abstract]
• Marina Madre*, Natella Panchenko, Alexander Golbraikh, Regina Zhuk, Upendra K. Pandit, Jan Geenevasen and Gerrit-Jan Koomen
  Purine Nucleoside Analogues. 11. An Alternative Synthesis of N- and O-Alkyl Derivatives of 9- and 7-[(2-Acetoxyethoxy)methyl]-N²-acetylguanine
  1999, Vol. 64, Issue 4, pp. 685–695 [Abstract]
• Shahriyar Taghavi-Moghadam, Rüdiger Stumpf, Helmut Fischer and Wolfgang Pfleiderer*
  Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5-b][1,4]diazepine-2,4(1H,3H)-diones
  1999, Vol. 64, Issue 2, pp. 313–320 [Abstract]
• Michal Hocek* and Antonín Holý
  Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues
  1999, Vol. 64, Issue 2, pp. 229–241 [Abstract]
• Hana Dvořáková, Dalimil Dvořák and Antonín Holý
  Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates
  1998, Vol. 63, Issue 12, pp. 2065–2074 [Abstract]
• Viktor Dražan and Vladimír Vetterl
  Adsorption and Condensation of Xanthine at the Mercury/Solution Interface
  1998, Vol. 63, Issue 12, pp. 1977–1993 [Abstract]

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